Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Ito, F.; Fu, Y.; Kao, S.A.; Yang, H.; Chen, X.S.
    Family-wide comparative analysis of cytidine and methylcytidine deamination by eleven human APOBEC proteins (2017), J. Mol. Biol., 429, 1787-1799 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.5.4.B9 expression in Escherichia coli Homo sapiens
3.5.4.38 expression in Escherichia coli Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.5.4.B9 Homo sapiens Q9HC16
-
-
3.5.4.38 Homo sapiens P31941
-
-
3.5.4.38 Homo sapiens Q6NTF7
-
-
3.5.4.38 Homo sapiens Q8IUX4
-
-
3.5.4.38 Homo sapiens Q96AK3
-
-
3.5.4.38 Homo sapiens Q9HC16
-
-
3.5.4.38 Homo sapiens Q9NRW3
-
-
3.5.4.38 Homo sapiens Q9UH17
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.5.4.B9
-
 Homo sapiens
3.5.4.38
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.4.B9 cytosine in single-stranded DNA + H2O relatively low deaminase activity and selectivity for methylated cytosine Homo sapiens uracil in single-stranded DNA + NH3
-
 ?
3.5.4.38 cytosine in single-stranded DNA + H2O deamination activity of methylated cytosine is demonstrated APOBEC3B Homo sapiens uracil in single-stranded DNA + NH3
-
 ?
3.5.4.38 cytosine in single-stranded DNA + H2O high deaminase activities on cytosine and methylated cytosine with relatively high selectivity for methylated cytosine Homo sapiens uracil in single-stranded DNA + NH3
-
 ?
3.5.4.38 cytosine in single-stranded DNA + H2O relatively low deaminase activity and selectivity for methylated cytosine Homo sapiens uracil in single-stranded DNA + NH3
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.5.4.B9 APOBEC3G
-
 Homo sapiens
3.5.4.38 APOBEC3A
-
 Homo sapiens
3.5.4.38 APOBEC3B
-
 Homo sapiens
3.5.4.38 APOBEC3C
-
 Homo sapiens
3.5.4.38 APOBEC3D
-
 Homo sapiens
3.5.4.38 APOBEC3F
-
 Homo sapiens
3.5.4.38 APOBEC3G
-
 Homo sapiens
3.5.4.38 APOBEC3H
-
 Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.5.4.B9 6.5
-
-
 Homo sapiens
3.5.4.38 5.5
-
-
 Homo sapiens
3.5.4.38 6.5
-
-
 Homo sapiens